Publications

2024

Suzuki, T.*, Ogizawa, A., Ishiguro, K. and Nagao, A.
Biogenesis and roles of tRNA queuosine modification and its glycosylated derivatives in human health and diseases
Cell Chem Biol., in press (2024) [Cell Chem Biol.]
Yamazaki, Y., Ito, T., Nakagawa, S., Sugihira, T., Villaruz, A. E., Ishiguro, K., Salcman, B., Li, S., Takada, S., Inohara, N., Kusuya, Y., Shibata, A., Tamai, M., Aoyama, R., Inoue, K., Murata, S., Matsushita, K., Miyabe, A., Taniguchi, T., Igari, H., Ishiwada, N., Taniguchi, M., Nakada, T., Matsue, H., Fujimoto, M., Hishiki, H., Osone, Y., Hamada, H., Shimojo, N., Suzuki, T., Otto, M., Núñez, G., Takahashi, H., Takaya, A., and Nakamura, Y.*
Altered Genomic Methylation Promotes Staphylococcus aureus Persistence in Hospital Environment
Nature Commun, in press (2024) [Nature Commun]
Gong, H.T., Sakaguchi, Y., Suzuki, T., Yanagisawa, M. and Aida, T.*
Near-identical macromolecules spontaneously partition into concentric circles
Nature, in press (2024) [Nature]
+Kurata, T., +Takegawa, M., Ohira, T., Syroegin, E.A., Atkinson, G.C., Johansson, M.JO, Polikanov, Y.S., Garcia-Pino, A., Suzuki, T.* and Hauryliuk, V.*
Toxic Small Alarmone Synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr
Science Advances, in press (2024) [Science Advances]
Akichika, S and Suzuki, T.*
Cap-specific m6Am modification: A transcriptional anti-terminator by sequestering PCF11 with implications for neuroblastoma therapy
Mol Cell, in press (2024) [Mol Cell]
Matsuura, J., Akichika, S., Wei, F.Y., Suzuki, T., Yamamoto, T., Watanabe, Y., Valášek, L. S., Mukasa, A., *Tomizawa, K., and Chujo, T.*
Human DUS1L catalyzes dihydrouridine modification at tRNA positions 16/17, and DUS1L overexpression perturbs translation
Commun. Biol., in press (2024) [Commun. Biol.]
Maharjan, S., Gamper, H., Yamaki, Y., Henley, R. Y., Li, N-S., Suzuki, T., Suzuki, T., Piccirilli, J. A., Wanunu, M., Seifert, E., Wallace, D. C., and Hou, Y-M.*
Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology
Nature Commun., in press (2024) [Nature Commun.]
Suzuki, T.*
Glycosylated tRNA modifications and their physiological functions
Glycofurum, in press (2024) [Glycofurum]
Miyauchi, K.+, Kimura, S.+, Akiyama, N.+, Inoue, K., Ishiguro, K., Vu, T.S., Srisuknimit, V., Koyama, K., Hayashi, G., Soma, A., Nagao, A., Shirouzu, M., Okamoto, A., *Waldor, M., and Suzuki, T.*
A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis
Nature Chem Biol., in press (2024) [Nature Chem Biol.]
Hidese, R., Ohira, T., Sakakibara, S., Suzuki, T., Shigi, N.* and Fujiwara, S.
Functional redundancy of ubiquitin-like sulfur-carrier proteins facilitates flexible, efficient sulfur utilization in the primordial archaeon Thermococcus kodakarensis
mBio, in press (2024) [mBio]
Liu, J, Yashiro, Y., Sakaguchi, Y., Suzuki, T. and Tomita, K.*
Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3
Nucleic Acids Res., in press (2024) [Nucleic Acids Res]
Yang, Y., Nakayama, K., Okada, S., Sato, K., Wada, T., Sakaguchi, Y., Murayama, A., Suzuki, T. and Sakurai, M.*
ICLAMP: A Novel Technique to Explore Adenosine Deamination via Inosine Chemical Labeling and Affinity Molecular Purification
FEBS Lett., in press (2024) [FEBS Lett]
Lu, W., Terasaka, N., Sakaguchi, Y., Suzuki, T., Suzuki, T. and Suga, H.*
An anticodon-sensing T-boxzyme generates the elongator nonproteinogenic aminoacyl-tRNA in situ of a custom-made translation system for incorporation
Nucleic Acids Res., in press (2024) [Nucleic Acids Res]
Akiyama, N., Ishiguro, K., Yokoyama, T., Miyauchi, K., Nagao, A., Shirouzu M. and Suzuki, T.*
Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine
Nat Struct Mol Biol, (2024) [Nat Struct Mol Biol]
Ohira, T. and Suzuki, T.*
Transfer RNA modifications and cellular thermotolerance
Mol Cell, 84, 94-106 (2024) [Mol Cell]

2023

+Zhao, X., +Ma, D., +Ishiguro, K., Saito, H., Akichika, S., Matsuzawa, I., Mito, M., Irie, T., Ishibashi, K., Wakabayashi, K., Sakaguchi, Y., Yokoyama, T., Mishima, Y., Shirouzu, M., Iwasaki, S., Suzuki, T.* and Suzuki, T.* + equal contribution
Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth
Cell, 186, 5517-5535 (2023) [Cell]
Soma, A.*, Kubota, A., Tomoe, D., Ikeuchi, Y., Kawamura, F., Arimoto, H., Shiwa, Y., Kanesaki, Y., Nanamiya, H., Yoshikawa, H., Suzuki, T. and Sekine, Y.
yaaJ, the tRNA-specific adenosine deaminase is dispensable in Bacillus subtilis
Genes, 14, 1515 (2023) [Genes]
Ueda, S., Yagi, M., Tomoda, E., Matsumoto, S., Ueyanagi, Y., Do, Y., Setoyama, D., Matsushima, Y., Nagao, A., Suzuki, T., Ide, T., Mori, Y., Oyama, N., Kang, D. and *Uchiumi, T.
Mitochondrial haplotype mutation alleviates respiratory defect of MELAS by restoring taurine modification in tRNA with 3243A>G mutation
Nucleic Acids Res., 51, 7480-7495 (2023) [Nucleic Acids Res.]
Nagao, A.*, Nakanishi, Y., Yamaguchi, Y., Mishina, Y., Karoji, M., Toya, T., Fujita, T., Iwasaki, S., Miyauchi, K., Sakaguchi, Y. and Suzuki, T.*
Quality control of protein synthesis in the early elongation stage
Nature Commun., 14, 2704 (2023) [Nature Commun.]
Suzuki, T.*, Yi, C.* and Song, J.
Wolf Prize in Chemistry 2023: A Celebration for Chemical Biology
ACS Chemical Biology, 18, 671-673 (2023) [ACS Chemical Biology]
Nakagawa, R., Hirano, H., Omura, S.N., Nety, S., Kannan, S., Altae-Tran, H., Yao, X., Sakaguchi, Y., Ohira, T., Wu, W.Y., Nakayama, H., Shuto, Y., Tanaka, T., Sano, F. K., Kusakizako, T., Kise, Y., Ito, Y., Dohmae, N., van der Oost, J., Suzuki, T., Zhang, F. and Nureki, N.*
Cryo-EM structure of the transposon-associated TnpB enzyme
Nature, 616, 390-397 (2023) [Nature]
Tomoda, E., Nagao, A.*, Shirai, Y., Asano, K., Suzuki, T., Battersby, B., and Suzuki, T.*
Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases
Nucleic Acids Res., 51(14):7563-7579 (2023) [Nucleic Acids Res.]
Ohno, H., Akamine, S., Mochizuki, M., Hayashi, K., Akichika, S., Suzuki, T. and Saito, H.*
Versatile strategy using vaccinia virus-capping enzyme to synthesize functional 5' cap-modified mRNAs
Nucleic Acids Res., 51(6):e34 (2023) [Nucleic Acids Res.]

2022

Pan, M., Zorbas, C., Sugaya, M., Ishiguro, K., Kato, M., Nishida, M., Zhang, H., Candeias, M.M., Okamoto, A., Ishikawa, T., Soga, T., Aburatani, H., Sakai, J., Matsumura, Y.,Suzuki, T., Proud, C.G., Lafontaine, D. L. J. and Osawa, T.*
Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors
Nature Commun., 13, 3706 (2022) [Nature Commun.]
Noda, Y., Okada, S. and Suzuki, T.*
Regulation of A-to-I RNA editing and stop codon recoding to control selenoprotein expression during skeletal myogenesis
Nature Commun., 13, 2503 (2022) [Nature Commun.]
Ohira, T.+,*, Minowa, K.+, Sugiyama, K., Yamashita, S., Sakaguchi, Y., Miyauchi, K., Noguchi, R., Kaneko, A., Orita, I., Fukui, T., Tomita, K.* and Suzuki, T.* + equal contribution
Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance
Nature, 605, 372-379(2022) [Nature]
Wang, J., Yashiro, Y., Sakaguchi, Y., Suzuki, T. and Tomita,K.*
Mechanistic insights into tRNA cleavage by a contact-dependent growth inhibitor protein and translation factors
Nucleic Acids Res., 50, 4713-4731(2022) [Nucleic Acids Res.]

2021

Ishigami, Y., Ohira, T., Isokawa, Y., Suzuki, Y. and Suzuki, T. *
A single m6A modification in U6 snRNA diversifies exon sequence at 5' splice site
Nature Commun., 12, 3244 (2021)
Akichika, S., Suzuki, T. and Suzuki, T.*
Mass spectrometric analysis of mRNA 5’ terminal modifications
Methods in Enzymol.,658, 407-418(2021)
Kurata, T.*, Brodiazhenko, T., Oliveira, S. R. A., Roghanian, M., Sakaguchi, Y., Turnbull, K. J., Bulvas, O., Takada, H., Taman, H., Ainelo, A., Pohl, R., Rejman, D., Tenson, T., Suzuki, T.., Garcia-Pino, A., Atkinson, G. C.* and Hauryliuk, V.*
RelA-SpoT Homologue toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis
Mol Cell, 81, 3160-3170 (2021)
Ninomiya, K., Iwakiri, J., Kharmis Aly, K., Sakaguchi, Y., Adachi, S., Natsume, T., Terai, G., Asai, K., Suzuki, T.. and Hirose, T.*
m6A modification of HSATIII IncRNAs regulates temperature-dependent splicing
EMBO J., 40, e107976 (2021)
Watabe, E., Togo-Ohno, M., Ishigami, Y., Wani, S., Hirota, K., Kimura-Asami, M., Hasan, S., Takei, S., Fukamizu, A., Suzuki, Y., Suzuki, T.. and Kuroyanagi, H.*
m6A-mediated alternative splicing coupled with nonsense-mediated mRNA decay regulates SAM synthetase homeostasis
EMBO J., 40, e106434 (2021)
Nagayoshi, Y., Chujo, T., Hirata, S., Nakatsuka, H., Chen, C.W., Takakura, M., Miyauchi, K., Ikeuchi, Y., Carlyle, B.C., Kitchen, R.R., Suzuki, T., Katsuoka, F., Yamamoto, M., Goto, Y., Tanaka, M., Natsume, K., Nairn, A.C., Suzuki, T., Tomizawa, K.* and Wei, F.Y.*
Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability
Science Advances, 7, eabf3072 (2021)
Futakuchi, A., Nagiri, C., Shihoya, W., Inoue, A., Aoki, J., Ito, Y., Suzuki, T., Suzuki, T., Inoue, T., Nureki, O., Tanihara, H., Tomizawa, K. and Wei, F.Y.*
N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand
Mol Cell, 81, 659-674 (2021)
Suzuki, T.
The expanding world of tRNA modifications and their disease relevance
Nature Reviews Molecular Cell Biology, 22, 375-392 (2021)
Ishigami, Y., Suzuki, T.* and Suzuki, T.*
Mass spectrometric analysis of mitochondrial RNA modifications
Methods in Mol Biol., 2192, 89-101 (2021)
Suzuki, T. and Nagao, A.
The genetic code and its variants
Encyclopedia of Life Sciences, 2, 147-157 (2021)

2020

Yashiro, Y., Sakaguchi, Y., Suzuki, T., and Tomita, K.*
Mechanism of specific aminoacyl-tRNA acetylation by an aminoacyl-tRNA acetyltransferase toxin from enterohemorrhagic E. coli
Nature Commun., 11, 5438 (2020)
Kurimoto, R., Chiba, T., Ito, Y., Matsushima, T., Yano, Y., Miyata, K., Suzuki, T., Tomita, K. and Asahara, H.
The tRNA pseudouridine synthase TruB1 regulates the maturation and function of let-7 miRNA
EMBO J., 39, e104708 (2020)
Suzuki, T., Yashiro, Y., Kikuchi, I., Ishigami, Y., Saito, H., Matsuzawa, I., Okada, S., Mito, M., Iwasaki, S., Ma, D., Zhao, X., Asano, K., Lin, H., Kirino, Y., Sakaguchi, Y. and Suzuki, T.
Complete chemical structures of human mitochondrial tRNAs
Nature Commun.,11, 4269 (2020)
Rossello-Tortella, M., Llinas-Arias, P., Sakaguchi, Y., Miyauchi, K., Davalos, V., Setien, F., Calleja-Cervantes, M., Pineyro, D., Martinez-Gomez, J., Guil, S., Joshi, R., Villanueva, A., Suzuki, T. and Esteller, M.*
Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer
Proc. Natl. Acad. Sci. USA.,117, 20785-20793 (2020)
Zhang, C., Yashiro, Y., Sakaguchi, Y., Suzuki, T. and Tomita, K.
Substrate specificities of Escherichia coli ItaT that acetylates aminoacyl-tRNAs
Nucleic Acids Res.,48, 7532-7544 (2020)
Abe, T., Nagai, R., Shimazaki, S., Kondo, S., Nishimura, S., Sakaguchi, Y., Suzuki, T., Imataka, H., Tomita, K. and Takeuchi-Tomita, N.
In vitro yeast reconstituted translation system reveals function of eIF5A for synthesis of long polypeptide
J. Biochem., 167, 451-462 (2020)
Nagao, T., Shintani, Y., Hayashi, T., Kioka, H., Kato, H., Nishida, Y., Yamazaki, S., Tsukamoto, O., Yashirogi, S., Yazawa, I., Asano, Y., Shinzawa-Itoh, K., Imamura, H., Suzuki, T., Suzuki, T., Goto, Y. and Takashima, S.
Higd1a improves respiratory function in the models of mitochondrial disorder
FASEB J. , 34, 1859-1871(2020)
Shigi, N., Horitani, M., Miyauchi, K., Suzuki, T. and Kuroki, M.
An ancient type of MnmA protein is an iron-sulfur cluster-dependent sulfurtransferase for tRNA anticodons
RNA , 26, 240-250 (2020)
Hojo, H., Yashiro, Y., Noda, Y., Ogami, K., Yamagishi, R., Okada, S., Hoshino, S. and Suzuki, T.
The RNA-binding protein QKI-7 recruits the poly(A) polymerase GLD-2 for 3’ adenylation and selective stabilization of microRNA-122
J. Biol. Chem. , 295, 390-402(2020)

2019

Akichika, S., Hirano, S., Nureki, O. and Suzuki, T.
Discovery of cap-specific adenosine-N6-methyltransferase (CAPAM)
SPring-8/SACLA Research Frontiers 3-4 (2019)
Takakura, M.+, Ishiguro, K.+, Akichika, S., Miyauchi, K. and Suzuki, T.
Biogenesis and functions of aminocarboxypropyluridine in tRNA
Nature Commun. (2019) [Nature Commun.]
Hirata, A., Suzuki, T., Nagano, T., Fujii, D., Okamoto, M., Sora, M., Lowe, T.M., Kanai, T., Atomi, H., Suzuki, T. and Hori, H.
Distinct modified nucleosides in tRNATrp from the hyperthermophilic archaeon Thermococcus kodakarensis and requirement of tRNA m2G10/m2,2G10 methyltransferase (archaeal Trm11) for survival at high temperatures
J. Bacterial., 201 (2019) [ DOI link.]
Shinoda, S.+, Kitagawa, S.+, Nakagawa, S., Wei, F., Tomizawa, K., Araki, K., Araki, M., Suzuki, T., and Suzuki, T.
Mammalian NSUN2 introduces 5-methylcytidines to mitochondrial tRNAs
Nucleic Acids Res.,8734?8745 (2019)
Sakai, Y.+, Kimura, S.+ and Suzuki, T.
Dual pathways of tRNA hydroxylation ensure efficient translation by expanding decoding capability
Nature Commun. (2019) [Nature Commun.]
Hayashi, S., Mori, S., Suzuki, T., Suzuki, T. and Yoshihisa, T.
Impact of intron removal from tRNA genes on Saccharomyces cerevisiae
Nucleic Acids Res., 5936?5949 (2019) [Nucleic Acids Res.]
Ishiguro, K., Arai, T. and Suzuki, T.
Depletion of S-adenosylmethionine impacts on ribosome biogenesis through hypomodification of a single rRNA methylation
Nucleic Acids Res.,4226?4239 (2019) [Nucleic Acids Res.]
Ishigami, Y., Suzuki, T. and Suzuki, T.
Mass spectrometric analysis of mitochondrial RNA modifications
Methods in Mol Biol. (2019)
Orita, I., Futatsuishi, R., Adachi, K., Kaneko, A., Minowa, K., Ohira, T., Suzuki, M., Tamura, T., Nakamura, S., Imanaka, T., Suzuki, T. and Fukui, T.
Random mutagenesis of a hyperthermophilic archaeon identified tRNA modifications associated with cellular hyperthermotolerance
Nucleic Acids Res. , 47, 1964-1976 (2019) [Nucleic Acids Res.]
Okada, S., Ueda, H., Noda, Y. and Suzuki, T.
Transcriptome-wide identification of A-to-I RNA editing sites with ICE-seq
Methods , 156, 66-78 (2019) [Methods]
Akichika, S., Hirano, S., Shichino, Y., Suzuki, T., Nishimasu, H., Ishitani, R., Sugita, A., Hirose, Y., Iwasaki, S., Nureki, O. and Suzuki, T. + equal contribution
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase
Science, 363, eaav0080 (2019) [Science] [F1000Prime]

2018

Taniguchi, T., Miyauchi, K., Sakaguchi, Y., Yamashita, S., Soma, A., Tomita, K. and Suzuki, T.
Acetate-dependent tRNA acetylation required for decoding fidelity in protein synthesis
Nature Chem Biol. , 14, 1010-1020 (2018)[Pubmed] [UTokyo focus]
Lin, H., Kenjyo, M., Harada, T., Okita, R., Takeshita, E., Komaki, H., Yagasaki, H., Fujioka, K., Goto, Y., Yanaka, K., Nakagawa, S., Sakaguchi, Y. and Suzuki, T.
CO2-sensitive tRNA modification associated with human mitochondrial disease
Nature Commun., 14, 9(1):1875 (2018)[Pubmed] [UTokyo Focus]
Oshima, T., Ishiguro, K., Suzuki, T. and Kawahara, Y.
Quantification of methylation efficiency at a specific N6-methyladenosine position in rRNA by using BNA probes
Chem. Commun. 54, 9627-9630 (2018)[Pubmed]
Matsuda, S., Yasukawa, T., Sakaguchi, Y., Ichiyanagi, K., Unoki, M., Gotoh, K., Fukuda, K., Sasaki, H., Suzuki, T. and Kang, D.
Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA
Sci. Rep. , 8(1):5801 (2018)[Pubmed]
Kudrin, P., Dzhygyr, I., Ishiguro, K., Beljantseva, J., Maksimova, E., Sofia Raquel Alves Oliveira, Varik, V., Payoe, R., Konevega, A., Tenson, T., Suzuki, T. and Hauryliuk, V.
The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA
Nucleic Acids Res., 46, 1973?1983(2018) [Pubmed]
Asano, K.+, Suzuki, T.+, Saito, A., Wei, F., Ikeuchi, Y., Numata, T., Tanaka, R., Yamane, Y., Yamamoto, T., Goto, T., Kishita, Y., Murayama, K., Ohtake, A., Okazaki, Y., Tomizawa, K., Sakaguchi, Y. and Suzuki, T.
Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease
Nucleic Acids Res., 46, 1565-1583 (2018) [Pubmed] + equal contribution, Awarded as a Breakthrough article
Fakruddin, M., Wei, F., Kaieda, T., Suzuki, T., Asano, K., Omori, A., Fujimura, A., Kaitsuka, T., Miyata, K., Araki, K., Oike, Y., Scorrano, L., Suzuki, T. and Tomizawa, K.
Defective mitochondrial tRNA taurine-modification activates global proteostress and leads to mitochondrial disease
Cell Reports, 22, 482-496 (2018) [Pubmed]

2017

Shima, H., Matsumoto, M., Ishigami, Y., Ebina, M., Muto, A., Sato, Y., Kumagai, S., Ochiai, K., Suzuki, T. and Igarashi, K.
S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1
Cell Reports, 21, 3354-3363 (2017) [Pubmed]
Kimura, S., Sakai, Y., Ishiguro, K. and Suzuki, T.
Biogenesis and iron-dependency of ribosomal RNA hydroxylation
Nucleic Acids Res., 45(22), 12974-12986 (2017) [Pubmed]
Chadani, Y., Niwa, T., Izumi, T., Sugita, N., Nagao, A., Suzuki, T., Chiba, S., Ito, K. and Taguchi, H.
Intrinsic ribosome destabilization underlies translation and provides an organism with a strategy of environmental sensing
Mol Cell, 68(3), 528-539.e5 [Pubmed]
Nagao, A., Ohara, M., Miyauchi, K., Yokobori, S., Yamagishi, A., Watanabe, K. and Suzuki, T.
Hydroxylation of a conserved tRNA modification establishes non-universal genetic code in echinoderm mitochondria
Nature Struct Mol Biol., advance online publication (2017)[Pubmed]
Chen, M., Asai, S., Narai, S., Nambu, S., Omura, N., Sakaguchi, Y., Suzuki, T., Ikeda-Saito, M., Watanabe, K., Yao, M., Shigi, N. and Tanaka, Y.
Biochemical and structural characterization of an oxygen-sensitive 2-thiouridine synthesis catalyzed by an iron-sulfur protein TtuA
Proc. Natl. Acad. Sci. USA., 114, 4954-4959 (2017) [Pubmed]
Kawarada, L., Suzuki, T., Ohira, T., Hirata, S., Miyauchi, K. and Suzuki, T.
ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications
Nucleic Acids Res., 45, 7401-7415 (2017) [Pubmed]
Sato, A., Suematsu, T., Aihara, K., Kita, K., Suzuki, T., Watanabe, K., Ohtsuki, T. and Watanabe, Y.
Duplication of Drosophila melanogaster mitochondrial EF-Tu: pre-adaptation to T-arm truncation and exclusion of bulky aminoacyl residues
Biochem. J., 474, 957-969 (2017) [Pubmed]
Martinez, A., Yamashita, S., Nagaike, T., Sakaguchi, Y., Suzuki, T. and Tomita, K.
Human BCDIN3D Methylates 5'-phosphate of Cytoplasmic Histidine Transfer RNA
Nucleic Acids Res., 45, 5423-5436 (2017) [Pubmed]
Uchida, H., Matsumura, S., Okada, S., Suzuki, T., Minami, T. and Ito, S.
RNA editing enzyme ADAR2 is required for neuropathic pain after peripheral nerve injury
FASEB J., 31, 1847-1855 (2017) [Pubmed]
Currie, M. A., Brown, G., Wong, A., Ohira, T., Sugiyama, K., Suzuki, T., Yakunin, A. F., and Jia, Z.
Structural and functional characterization of the TYW3/Taw3 class of SAM-dependent methyltransferases
RNA, 23, 346-354 (2017) [Pubmed]
Kang, B.+, Miyauchi, K.+, Matuszewski, M., D’Almeida, G. S., Rubio, M., Alfonzo, J. D., Inoue, K., Sakaguchi, Y., Suzuki, T., Sochacka, E. and Suzuki, T.
Identification of 2-methylthio cyclic N⁶-threonylcarbamoyladenosine (ms²ct⁶A) as a novel RNA modification at position 37 of tRNAs
Nucleic Acids Res., 45, 2124-2136 (2017) [Pubmed] + equal contribution
Matuszewski, M., Wojciechowski, J., Miyauchi, K., Gdaniec, Z., Wolf, W. M., Suzuki, T. and Sochacka, E.
A hydantoin isoform of cyclic N⁶-threonylcarbamoyladenosine (ct⁶A) is present in tRNAs
Nucleic Acids Res., 45, 2137-2149 (2017) [Pubmed]

2016

Wu, Y., Wei, F-Y, Kawarada, L., Suzuki, T., Araki, K., Fujimura, A., Kaitsuka, T., Oike, Y., Suzuki, T., and Tomizawa, K.
Mtu1-mediated thiouridine formation of mitochondrial tRNAs is required for mitochondrial translation and is involved in reversible infantile liver
PLOS Genet., 12(9), e1006355 (2016) [Pubmed]
Bar-Yaacov, D., Frumkin, I., Yashiro, Y., Chujo, T., Ishigami, Y., Chemla, Y., Blumberg, A., Schlesinger, O., Bieri, P., Greber, B., Ban, N., Zarivach, R., Alfonta, L., Pilpel, Y., Suzuki, T. and Mishmar, D.
Mitochondrial 16S rRNA is methylated by tRNA methyltransferase TRMT61B in all vertebrates
PLOS Biol., 14(9), e1002557 (2016) [Pubmed]
Ohira, T. and Suzuki, T.
Precursors of tRNAs are stabilized by methylguanosine cap structures
Nature Chem Biol., 12, 648-655 (2016) [Pubmed]
Nakano, S.+, Suzuki, T.+, Kawarada, L., Iwata, H., Asano, K. and Suzuki, T.
NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNAMet
Nature Chem Biol., 12, 546-551 (2016) [Pubmed] + equal contribution
Frye, M., Jaffrey, S., Pan, T., Rechavi, G. and Suzuki, T.
RNA modifications: what have we learned and where are we headed?
Nature Rev Genet., 17, 365-372 (2016) [Pubmed]
Izumi, N., Shoji, K., Sakaguchi, Y., Honda, S., Kirino, Y., Suzuki, T., Katsuma, S. and Tomari, Y.
Identification and Functional Analysis of the Pre-piRNA 3' Trimmer in Silkworms
Cell, 164, 962-973 (2016) [Pubmed]
Sakai, Y., Miyauchi, K., Kimura, S., & Suzuki, T.
Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons
Nucleic Acids Res., 44, 509-523 (2016) [Pubmed]
Kohda, M., Tokuzawa, Y., Kishita, Y., Moriyama, Y., Mizuno, Y., Hirata, T., Yatsuka, Y., Yamashita-Sugahara, Y., Nakachi, Y., Kato, H., Okuda, A., Tamaru, S., Nyuzuki, H., Borna, N. N., Banshoya, K., Aigaki, T., Sato-Miyata, Y., Ohnuma, K., Suzuki, T., Nagao, A., Maehata, H., Matsuda, F., Higasa, K., Nagasaki, M., Yasuda, J., Yamamoto, M., Harashima, H., Yamazaki, H., Mori, M., Murayama, K., Ohtake, A. and Okazaki, Y.
A comprehensive genomic analysis reveals the genetic landscape of mitochondrial respiratory chain complex deficiencies
PLOS Genet., 12(1), e1005679 (2016) [Pubmed]

2015

Arai, T., Ishiguro, K., Kimura, S., Sakaguchi, Y., Suzuki, T. and Suzuki, T.
A single methylation of 23S rRNA triggers late steps of 50S ribosomal
subunit assembly
Proc. Natl. Acad. Sci. USA., 112, E4707-E4716 (2015) [Pubmed]
Katoh, T., Hojo, H. and Suzuki, T.
Destabilization of microRNA-122 in human cells by 3' deadenylation mediated
by PARN and CUGBP1
Nucleic Acids Res., 43, 7521-7534 (2015) [Pubmed]
Shoji, T., Takaya, A., Sato, Y., Kimura, S., Suzuki, T. and Yamamoto, T.
RlmCD-mediated U747 methylation promotes efficient G748 methylation by
methyltransferase RlmAII in 23S rRNA in Streptococcus pneumoniae; interplay
between two rRNA methylations responsible for telithromycin susceptibility
Nucleic Acids Res., 43, 8964-8972 (2015) [Pubmed]
Kyuma, T., Kimura, S., Hanada, Y., Suzuki, T., Sekimizu, K. and Kaito, C.
Ribosomal RNA methyltransferases contribute to Staphylococcus aureus virulence
FEBS J., 282, 2570-2584 (2015) [Pubmed]
Sakaguchi, Y., Miyauchi, K., Kang, B. and Suzuki, T.
Nucleoside analysis by hydrophilic interaction liquid chromatography coupled with mass spectrometry
Methods in Enzymol., 560, 19-28 (2015) [Pubmed]
Okada, S., Sakurai, M., Ueda, H. and Suzuki, T.
Biochemical and transcriptome-wide identification of A-to-I RNA editing sites by ICE-seq
Methods in Enzymol., 10, 715-732 (2015) [Pubmed]
Iwasaki, S., Sasaki, H. M., Sakaguchi, Y., Suzuki, T., Tadakuma, H. and Tomari, Y.
Defining fundamental steps in the assembly of Drosophila RNAi enzyme complex
Nature, 521, 533-536 (2015) [Pubmed]
Wei, F., Zhou, B., Suzuki, T., Miyata, K., Ujihara, Y., Takahashi, N., Xie, P., Michiue, H., Fujimura, A., Kaitsuka, T., Matsui, H., Koga, Y., Mohri, S., Suzuki, T., Oike, Y. and Tomizawa, K.
Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs precise
mitochondrial protein translation and contributes to myopathy in mice and humans
Cell Metab., 21, 428-442 (2015) [Pubmed]
Suzuki, T., Ueda, H., Okada, S. and Sakurai, M.
Transcriptome-wide identification of adenosine-to-inosine editing
using the ICE-seq method
Nature Protocol, 10, 715-732 (2015) [Pubmed]
Yoshida, M., Kataoka, N., Miyauchi, K., Ohe, K., Iida, K., Yoshida, S., Nojima, T., Okuno, Y., Onogi, H., Usui, T., Takeuchi, A., Hosoya, T., Suzuki, T. and Hagiwara, M.
Rectifier of aberrant mRNA splicing recovers tRNA modification in
familial dysautonomia
Proc. Natl. Acad. Sci. USA., 112, 2764-2769 (2015) [Pubmed]
Kimura, S. and Suzuki, T.
Iron-sulfur proteins responsible for RNA modifications
Biochim Biophys Acta., 1853, 1272-1283 (2015) [Pubmed]
Ishida, K., Miyauchi, K., Kimura, Y., Mito, M., Okada, S., Suzuki, T. and Nakagawa, S.
Regulation of gene expression via retrotransposon insertions and the noncoding RNA 4.5S RNAH
Genes Cells., 20, 887-901 (2015) [Pubmed]

2014

Ito, S., Horikawa, S., Suzuki, T., Kawauchi, H., Tanaka, Y., Suzuki, T. and Suzuki, T.
Human NAT10 is an ATP-dependent RNA acetyltransferase responsible for
N4-acetylcytidine formation in 18S rRNA
J. Biol. Chem. 289, 35724-35730 (2014) [Pubmed]
Suzuki, T. and Numata, T.
Convergent evolution of AUA decoding in bacteria and archaea
RNA Biol., 11, 1586-1596 (2014) [Pubmed]
Takai, H., Masuda, K., Sato, T., Sakaguchi, Y., Suzuki, T., Suzuki, T., Koyama-Nasu, R., Nasu-Nishimura, Y., Katou, Y., Ogawa, H., Morishita, Y., Kozuka-Hata, H., Oyama, M., Todo, T., Ino, Y., Mukasa, A., Saito, N., Toyoshima, C., Shirahige, K. and Akiyama, T.
5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome Complex
Cell Reports 9, 48-60 (2014) [Pubmed]
Ito, S., Akamatsu, Y., Noma, A., Kimura, S., Miyauchi, K., Ikeuchi, Y., Suzuki, T. and Suzuki, T.
A single acetylation of 18S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae
J. Biol. Chem. 289, 26201-26212 (2014) [Pubmed]
Kimura, S., Miyauchi, K., Ikeuchi, Y., Thiaville, P.C., de Crecy-Lagard, V. and Suzuki, T.
Discovery of the β-barrel?type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs
Nucleic Acids Res. 42, 9350-9365 (2014) [Pubmed]
Suzuki, T. and Suzuki, T.
A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
Nucleic Acids Res. 42, 7346-7357 (2014) [Pubmed]
Bhaskaran, H., Taniguchi, T., Suzuki, T., Suzuki, T. and Perona, J. J.
Structural dynamics of a mitochondrial tRNA possessing weak thermodynamic stability
Biochemistry, 53, 1456-1465 (2014) [Pubmed]
Sakurai, M., Ueda, H., Yano, T., Okada, S., Terajima, H., Mitsuyama, T., Toyoda, A., Fujiyama, A., Kawabata, H. and Suzuki, T.
A biochemical landscape of A-to-I RNA editing in the human brain transcriptome
Genome Res, 24, 522-534 (2014) [Pubmed]
Suzuki, T., Miyauchi, K., Sakaguchi, Y. and Suzuki, T.
Biochemical and mass spectrometric analysis of 3'-end methylation of piRNAs
Methods in Mol Biol, 1093, 59-72 (2014) [Pubmed]

2013

Yoda, M., Cifuentes, D., Izumi, N., Sakaguchi, Y., Suzuki, T., Giraldez, A.J. and Tomari, Y.
Poly(A)-specific ribonuclease mediates 3'-end trimming of Argonaute2-cleaved precursor microRNAs
Cell Reports, 14, 715-726 (2013) [Pubmed]
Tomikawa, C., Ohira, T., Inoue, Y., Kawamura, T., Yamagishi, A., Suzuki, T. and Hori, H.
Distinct tRNA modifications in the thermo-acidophilic archaeon, Thermoplasma acidophilum
FEBS Lett., 587, 3575-3580 (2013) [Pubmed]
Xie, P., Wei, F.-Y., Hirata, S., Kaitsuka, T., Suzuki, T., Suzuki, T. and Tomizawa, K.
Measurement of tRNA 2-methylthio modification by quantitative PCR for assessing type 2 diabetes risk
Clinical Chemistry, 59, 1604-1612 (2013) [Pubmed]
Taniguchi, T., Miyauchi, K., Nakane, D., Miyata, M., Muto, A., Nishimura, S. and Suzuki, T.
Decoding system for the AUA codon by tRNA^Ile with the UAU anticodon in Mycoplasma mobile
Nucleic Acids Res., 41, 2621-2631 (2013) [Pubmed]
Miyauchi, K., Kimura, S. and Suzuki, T.
A cyclic form of N⁶-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification
Nature Chem Biol., 9, 105-111 (2013) [Pubmed]
Ohira, T., Suzuki, T., Miyauchi, K., Suzuki, T., Yokobori, S., Yamagishi, A. and Watanabe, K.
Decoding mechanism of non-universal genetic codes in Loligo bleekeri mitochondria
J. Biol. Chem., 288, 7645-7652 (2013) [Pubmed]
Kita, S., Tanaka, Y., Hirano, N., Kimura, S., Suzuki, T., Suzuki, T., Yao, M. and Tanaka, I.
Crystal structure of a putative methyltransferase SAV1081 from Staphylococcus aureus
Protein & Peptide Letters, 20, 530-537 (2013) [Pubmed]

2012

Chujo, T. and Suzuki, T.
Trmt61B is a methyltransferase responsible for 1-methyladenosine at position 58 of human mitochondrial tRNAs
RNA,18, 2269-2276 (2012) [Pubmed]
Rodriguez, V., Vasudevan, S., Noma, A., Carlson, B.A., Green, J.E., Suzuki, T. and Chandrasekharappa, SC.
Structure-function analysis of human TYW2 enzyme required for the biosynthesis of a highly modified wybutosine (yW) base in phenylalanine-tRNA
PLoS ONE, 7(6):e39297 (2012) [Pubmed]
Chujo, T., Ohira, T., Sakaguchi, Y., Goshima, N., Nomura, N., Nagao, A. and Suzuki, T.
LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria
Nucleic Acids Res., 40, 8033-8047 (2012) [Pubmed]
Kimura, S., Ikeuchi, Y., Kitahara, K., Sakaguchi, Y., Suzuki, T. and Suzuki, T.
Base methylations in the double-stranded RNA by a fused methyltransferase bearing unwinding activity
Nucleic Acids Res., 40, 4071-4085 (2012) [Pubmed]
Higa-Nakamine, S., Suzuki, T., Uechi, T., Chakraborty, A., Nakajima, Y., Nakamura, M., Hirano, N., Suzuki, T. and Kenmochi, N.
Loss of snoRNA impairs ribosomal RNA modification and causes developmental defects in zebrafish
Nucleic Acids Res., 40, 391-398 (2012) [Pubmed]

2011

Yu, F., Tanaka, Y., Yamashita, K., Suzuki, T., Nakamura, A., Hirano, N., Suzuki, T., Yao, M. and Tanaka, I.
Molecular basis of dihydrouridine formation on tRNA
Proc. Natl. Acad. Sci. USA., 108, 19593-19598 (2011) [Pubmed]
Osawa, T., Inanaga, H., Kimura, S., Terasaka, N., Suzuki, T. and Numata, T.
Crystallization and preliminary X-ray diffraction analysis of an archaeal tRNA modification enzyme TiaS complexed with tRNA^Ile2 and ATP
Acta Crystallograph Sect F Struct Biol Cryst Commun., 67, 1414-1416 (2011) [Pubmed]
Osawa, T., Terasaka, N., Kimura, S., Inanaga, H., Suzuki, T. and Numata, T.
Structural basis of tRNA agmatinylation essential for AUA codon decoding
Nature Struct Mol Biol., 18, 1275-1280 (2011) [Pubmed]
Terasaka, N., Kimura, S., Osawa, T., Numata, T. and Suzuki, T.
Biogenesis of 2-agmatinylcytidine catalyzed by the dual protein and RNA kinase TiaS
Nature Struct Mol Biol., 18, 1268-1274 (2011) [Pubmed]
Suzuki, T., Miyauchi, K., Suzuki, T., Yokobori, S., Shigi, N., Kondow, A., Takeuchi, N., Yamagishi, A. and Watanabe, K.
Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria
J. Biol. Chem., 286, 35494-35498 (2011) [Pubmed]
Suzuki, T., Nagao, A. and Suzuki, T.
Human mitochondrial tRNAs: biogenesis, function, structural aspects and diseases
Annu Rev Genet., 45, 299-329(2011) [Pubmed]
Wei, F., Suzuki, T., Watanabe, S., Kimura, S., Kaistuka, T., Fujimura, A., Matsui, H., Atta, M., Fontecave, M., Yamagata, K., Suzuki, T. and Tomizawa, K.
Deficit of Lys-tRNA Modification by Cdkal1 Causes the Development of Type 2 Diabetes in Mice
J. Clin. Invest., 121, 3598-608 (2011) [Pubmed]
Ohira, T. and Suzuki, T.
Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast
Proc. Natl. Acad. Sci. USA., 108, 10502-10507 (2011) [Pubmed]
Noma, A., Yi, S., Katoh, T., Takai, Y., Suzuki, T. and Suzuki, T.
Actin-binding protein ABP140 is a methyltransferase responsible for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae
RNA, 17, 1111-1119 (2011) [Pubmed]
Suzuki, T. , Nagao, A. and Suzuki, T.
Human mitochondrial diseases caused by lack of taurine-modification in mitochondrial tRNAs
WIREs RNA., 2, 376-386 (2011) [Pubmed]
Bonneford, L., Arai, T., Sakaguchi, Y., Suzuki, T., Ishitani, R. and Nureki, O.
Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog
Proc. Natl. Acad. Sci. USA., 108, 3912-3917 (2011) [Pubmed]
Kato, M., Araiso, Y., Noma, A., Nagao, A., Suzuki, T., Ishitani, R. and Nureki, O.
Crystal structure of a novel jmjC-domain-containing protein, TYW5, involved in tRNA modification
Nucleic Acids Res., 39, 1576-1585 (2011) [Pubmed]
Sakurai, M. and Suzuki, T.
A biochemical identification of A-to-I RNA editing sites by the Inosine Chemical Erasing (ICE) method
Methods in Mol Biol, 718, 89-99 (2011) [Pubmed]

2010

Sakurai, M., Yano, T., Kawabata, H., Ueda, H. and Suzuki, T.
Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome
Nature Chem Biol., 6, 733-740 (2010) [Pubmed]
Ikeuchi, Y., Kimura, S., Numata, T., Nakamura, D., Yokogawa, T., Ogata, T., Wada, T., Suzuki, T. and Suzuki, T.
Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea
Nature Chem Biol., 6, 277-282 (2010) [Pubmed]
Noma, A., Ishitani, R., Kato, M., Nagao, A., Nureki, O. and Suzuki, T.
Expanding role of the Jumonji C domain as an RNA hydroxylase
J. Biol. Chem.,285, 34503-34507 (2010) [Pubmed]
Zhou, X., Zuo, Z., Zhou, F., Zhao, W., Sakaguchi, Y., Suzuki, T., Suzuki, T., Cheng, H. and Zhou, R.
Profiling sex-specific piRNAs in Zebrafish
Genetics, 186, 1175-1185 (2010) [Pubmed]
Mimaki, M., Hatakeyama, H., Komaki, H., Yokoyama, M., Arai, H., Kirino, Y., Suzuki, T., Nishino, I., Nonaka, I. and Goto, Y.
Reversible infantile respiratory chain deficiency: a clinical and molecular study
Annals of Neurology,68,845-854 (2010) [Pubmed]
Iwasaki, S., Kobayashi, M., Yoda, M., Sakaguchi, Y., Suzuki, T. and Tomari, Y.
Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC-loading of small RNA duplexes
Mol Cell, 39, 292-299 (2010) [Pubmed]
Kimura, S. and Suzuki, T.
Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA
Nucleic Acids Res., 38, 1341-1352 (2010) [Pubmed]
Suzuki, T. and Miyauchi, K.
Discovery and characterization of tRNA^Ile lysidine synthetase (TilS)
FEBS Lett., 584, 272-277 (2010) [Pubmed]

2009

Shoji, M., Tanaka, T., Hosokawa, M., Reuter, M., Stark, A., Kato, Y., Kondoh, G., Okawa, K., Chujo, T., Suzuki, T., Hata, K., Martin, S. L.,Noce, T., Kuramochi-Miyagawa, S., Nakano, T., Sasaki, H., Pillai, R. S., and Nakatsuji, N. and Chuma, S.
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline
Dev Cell, 17, 775-787 (2009) [Pubmed]
Nakanishi, K., Bonnefond, L., Kimura, S., Suzuki, T., Ishitani, R. and Nureki, O.
Structural basis for translational fidelity ensured by tRNA lysidine synthetase
Nature, 461, 1144-1148 (2009) [Pubmed]
Messmer, M., Putz, J., Suzuki, T., Suzuki, T., Sauter, C., Sissler, M. and Florentz, C.
Tertiary network in mammalian mitochondrial tRNA^Asp revealed by solution probing and phylogeny
Nucleic Acids Res., 37, 6881-6895 (2009) [Pubmed]
Nagao, A., Suzuki, T., Katoh, T., Sakaguchi, Y. and Suzuki, T.
Biogenesis of glutaminyl-mt tRNA^Gln in human mitochondria
Proc. Natl. Acad. Sci. USA., 106, 16209-16214 (2009) [Pubmed]
Umitsu, M., Nishimasu, H., Noma, A., Suzuki, T., Ishitani, R. and Nureki, O.
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2
Proc. Natl. Acad. Sci. USA., 106, 15616-15621 (2009) [Pubmed]
Valente, L., Shigi, N., Suzuki, T. and Zeviani, M.
The R336Q mutation in human mitochondrial EFTu prevents the formation of an active mt-EFTu•GTP•aa-tRNA ternary complex
Biochim Biophys Acta., 1792, 791-795 (2009) [Pubmed]
Awai, T., Kimura, S., Tomikawa, C., Ochi, A., Ihsanawati, I., Bessho, Y., Yokoyama, S., Ohno, S., Nishikawa, K., Yokogawa, T., Suzuki, T., Hori, H.
Aquifex aeolicus tRNA (N², N²-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA
J. Biol. Chem., 284, 20467-20478 (2009) [Pubmed]
Kitahara, K. and Suzuki, T.
The ordered transcription of RNA domains is not essential for ribosome biogenesis
Mol Cell, 34, 760-766 (2009) [Pubmed]
Suzuki, Y., Noma, A., Suzuki, T., Ishitani, R. and Nureki, O.
Structural basis of tRNA modification with CO₂ fixation and methylation by wybutosine synthesizing enzyme TYW4
Nucleic Acids Res., 37, 2910-2915 (2009) [Pubmed]
Chimnaronk, S., Suzuki, T., Manita, T., Ikeuchi, Y., Yao, M., Suzuki, T. and Tanaka, I.
RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon
EMBO J., 28, 1362-1373 (2009) [Pubmed]
Ogata, T., Shimazaki, T., Umemoto, T., Kurata, S., Ohtsuki, T., Suzuki, T. and Wada, T.
Chemical synthesis and properties of 5-taurinomethyluridine and 5-taurinomethyl-2-thiouridine
J. Org. Chem., 74, 2585-2588 (2009) [Pubmed]
Katoh, T., Sakaguchi, Y., Miyauchi, K., Suzuki, T., Kashiwabara, S., Baba, T. and Suzuki, T.
Selective stabilization of mammalian microRNAs by 3'-adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2
Genes Dev., 23, 433-438 (2009) [Pubmed]
Noma, A., Shigi, N. and Suzuki, T.
Biogenesis and functions of thio-compounds in transfer RNA: comparison of bacterial and eukaryotic thiolation machineries
DNA and RNA modification enzymes (Book LANDES), Chapter 27, 392-405 (2009) [about...]
Noma, A., Sakaguchi, Y. and Suzuki, T.
Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions
Nucleic Acids Res., 37, 1335-1352 (2009) [Pubmed]

2008

Shigi, N., Sakaguchi, Y., Asai, S., Suzuki, T. and Watanabe, K. Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors
EMBO J., 27, 3267-3278 (2008) [Pubmed]
Ikeuchi, Y., Kitahara, K. and Suzuki, T. The RNA acetyltransferase driven by ATP hydrolysis synthesizes N⁴-acetylcytidine of tRNA anticodon
EMBO J., 27, 2194-2203 (2008) [Pubmed]
Nagao, A., Shigi-Hino, N. and Suzuki, T. Measuring mRNA decay in human mitochondria
Methods Enzymol., 447, 489-499 (2008) [Pubmed]
Yokoyama, T. and Suzuki, T. Ribosomal RNAs are tolerant toward genetic insertions: Evolutionary origin of the expansion segments
Nucleic Acids Res., 36, 3539-3551 (2008) [Pubmed]
Kurata, S., Weixlbaumer, A., Ohtsuki, T., Shimazaki, T., Wada, T., Kirino, Y., Takai, K., Watanabe, K. Ramakrishnan, V. and Suzuki, T. Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U•G wobble pairing during decoding
J. Biol. Chem., 283, 18801-18811 (2008) [Pubmed]

2007

Funakoshi, Y., Doi, Y., Hosoda, N., Uchida, N., Osawa, M., Shimada, I., Tsujimoto, M., Suzuki, T., Katada, T. and Hoshino, S. Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases
Genes Dev., 21, 3135-3148 (2007) [Pubmed]
Watanabe, K. and Suzuki, T. Universal genetic code and its natural variations
the Encyclopedia of Life Science, (Macmillan Publishers Ltd), in press (2007)
Tsutsumi, S., Sugiura, R., Ma, Y., Tokuoka, H., Ohta, K., Ohte, R., Noma, A., Suzuki, T. and Kuno, T. (2007) Wobble inosine tRNA modification is essential for cell cycle progression in G1/S and G2/M transitions in fission yeast
J. Biol. Chem., 282, 33459-33465. [Pubmed]
Suzuki, Y., Noma, A., Suzuki, T., Senda, M., Senda, T., Ishitani, R. and Nureki, O Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA
J. Mol. Biol., 372, 1204-1214 (2007) [Pubmed]
Saito, K., Sakaguchi, Y., Suzuki, T., Suzuki, T., Siomi, H. and Siomi, M.C. Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi-interacting RNAs at their 3' ends
Genes Dev., 21, 1603-1608 (2007) [Pubmed]
Kitahara, K., Kajiura, A., Sato, N.S. and Suzuki, T. Functional genetic selection of Helix 66 in Escherichia coli 23S rRNA identified the eukaryotic class of binding sequences for ribosomal protein L2
Nucleic Acids Res., 35, 4018-4029 (2007) [Pubmed]
Suzuki, T., Sakaguchi, Y. and Suzuki, T. Mass spectrometric analysis of 3'-terminal nucleosides in non-coding RNAs
Nat Protoc., DOI: 10.1038/nprot.2007.185 (2007) [Epub]
Ohara, T., Sakaguchi, Y., Suzuki, T., Ueda, H., Miyauchi, K. and Suzuki, T. The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated
Nat Struct Mol Biol., 14, 349-350 (2007) [Pubmed]
Dunham, C.M., Selmer, M., Phelps, S.S., Suzuki, T., Joseph, S. and Ramakrishnan, V. Structures of tRNAs with an expanded anticodon loop in the decoding center of the 30S Ribosomal Subunit
RNA, 13, 817-823 (2007) [Pubmed]
Nakai, Y., Nakai, M., Lill, R., Suzuki, T. and Hayashi, H. Thio modification of yeast cytosolic tRNA is an iron-sulfur protein-dependent pathway
Mol Cell Biol., 27, 2841-2847 (2007) [Pubmed]
Suzuki, T. and Suzuki, T. Chaplet column chromatography: isolation of a large set of individual RNAs in a single step.
Methods Enzymol., 425, 231-239 (2007) [Pubmed]
Suzuki, T., Ikeuchi, Y., Noma, A., Suzuki, T. and Sakaguchi, Y. Mass spectrometric identification and characterization of RNA-modifying enzymes.
Methods Enzymol., 425, 211-229 (2007) [Pubmed]
Miyauchi, K., Ohara, T. and Suzuki, T. Automated parallel isolation of multiple species of non-coding RNAs by the reciprocal circulating chromatography method
Nucleic Acids Res., 35, e24 (2007) [Pubmed]
Katoh, T. and Suzuki, T. Specific residues at every third position of siRNA shape its efficient RNAi activity
Nucleic Acids Res., 35, e27 (2007) [Pubmed / Epub][siExplorer]

2006

Sato, N.S., Hirabayashi, N., Agmon, I., Yonath, A. and Suzuki, T. Comprehensive genetic selection revealed bases essential for protein synthesis in the peptidyl-transferase center.
Proc. Natl. Acad. Sci. USA., 103, 15386-15391 (2006) [Pubmed]
Komoda, T., Sato, N.S., Phelps, S.S., Namba, N., Joseph, S. and Suzuki, T. The A-site finger in 23S rRNA acts as a functional attenuator for translocation
J. Biol. Chem., 281, 32303-32309 (2006) [Pubmed]
Takeda, H., Toyooka, T., Ikeuchi, Y., Yokobori, S., Okadome, K., Takano, F., Oshima, T., Suzuki, T., Endo, Y. and Hori, H. The substrate specificity of tRNA (m¹G37) methyltransferase (TrmD) from Aquifex aeolicus.
Genes Cells, 11, 1353-1365 (2006) [Pubmed]
Sato, A., Watanabe, Y., Suzuki, T., Komiyama, M., Watanabe, K. and Ohtsuki, T. Identification of the residues involved in the unique serine specificity of Caenorhabditis elegans mitochondrial EF-Tu2.
Biochemistry, 45, 10920-10927 (2006) [Pubmed]
Numata, T., Ikeuchi, Y., Fukai, S., Suzuki, T. and Nureki, O. Snapshots of tRNA sulfuration via an adenylated intermediate
Nature, 442, 419-424 (2006) [Pubmed]
Guan, M.X., Yan, Q., Li, X., Bykhovskaya, Y., Gallo-Teran, J., Hajek, P., Umeda, N., Zhao, H., Garrido, G., Mengesha, E., Suzuki, T., del Castillo, I., Peters, J. L., Li, R., Qian, Y., Wang, X., Shohat, M., Estivill, X., Watanabe, K. and Fischel-Ghodsian, N. Mutation in TRMU related to mitochondrial tRNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutations
Am J Hum Genet., 79, 291-302 (2006) [Pubmed]
Numata, T., Ikeuchi, Y., Fukai, S., Adachi, H., Matsumura, H., Takano, K., Murakami, S., Inoue, T., Mori, Y., Sasaki, T., Suzuki, T. and Nureki, O. Crystallization and preliminary X-ray analysis of the tRNA thiolation enzyme MnmA from Escherichia coli complexed with tRNA^Glu.
Acta Crystallograph Sect F Struct Biol Cryst Commun., 62, 368-371 (2006) [Pubmed]
Hirabayashi, N., Sato, N.S. and Suzuki, T. Conserved loop sequence of helix 69 in Escherichia coli 23S rRNA is involved in the A-site tRNA binding and translational fidelity
J. Biol. Chem, 281, 17203-17211 (2006) [Pubmed]
Noma, A., Kirino, Y., Ikeuchi, Y. and Suzuki, T. Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA
EMBO J., 25, 2142-2154 (2006) [Pubmed]
Kirino, Y., Yasukawa, T., Marjavaara, S.K., Jacobs, H.T., Holt, I.J., Watanabe, K. and Suzuki, T. Acquisition of the wobble modification in mitochondrial tRNA^Leu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect
Hum Mol Genet., 15, 897-904 (2006) [Pubmed]
Takano, Y., Takayanagi, N., Hori, H., Ikeuchi, Y., Suzuki, T., Kimura, A. and Okuno, T. A gene involved in modification of transfer RNA is required for fungal pathogenicity and stress tolerance of Colletotrichum lagenarium.
Mol Microbiol., 60, 81-92 (2006) [Pubmed]
Shigi, N., Sakaguchi, Y., Suzuki, T. and Watanabe, K. Identification of two tRNA-thiolation genes required for cell growth at extremely high temperatures
J. Biol. Chem., 281, 14296-14306 (2006) [Pubmed]
Shigi, N., Suzuki, T., Terada, T., Shirouzu, M., Yokoyama, S. and Watanabe, K. Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA
J. Biol. Chem., 281, 2104-2113 (2006) [Pubmed]
Numata, T., Fukai, S., Ikeuchi, Y., Suzuki, T. and Nureki, O. Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex
Structure, 14, 357-366 (2006) [Pubmed]
Ikeuchi, Y., Shigi, N. Kato, J., Nishimura, A. and Suzuki, T. Mechanistic insights into sulfur-relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions
Mol Cell., 21, 97-108 (2006) [Pubmed]

Symposium series

Noma, A. and Suzuki, T.
Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis
Nucleic Acids Symp Ser (Oxf), 50, 65-66 (2006)
Kitahara, K., Sato, N. S., Namba, N., Yokota, T., Tsujimura, T. and Suzuki, T.
Systematic deletion of rRNAs for investigating ribosome architecture and function
Nucleic Acids Symp Ser (Oxf), 50, 287-288 (2006)
Kirino, Y., Yasukawa, T., Suzuki, T., Suzuki, T. and Watanabe, K.
Molecular mechanism of MELAS caused by Taurine-modification defect in mitochondrial tRNA
Third International Congress on Vascular Dementia, p69-73 (2003)
Katoh, T., Susa, M., Suzuki, T., Umeda, N., Watanabe, K. and Suzuki, T.
Simple and rapid synthesis of siRNA derived from in vitro transcribed shRNA.
Nucleic Acids Research Supplement, 3, 249-250 (2003)
Kurata, S., Ohtsuki, T., Wada, T., Kirino, Y., Takai, K., Saigo, K., Watanabe, K. and Suzuki, T.
Decoding property of C5 uridine modification at the wobble position of tRNA anticodon.
Nucleic Acids Research Supplement, 3, 245-246 (2003)
Zhang, L., Sato, N. S., Watanabe, K. and Suzuki, T.
Functional genetic selection of the decoding center in E. coli 16S rRNA.
Nucleic Acids Research Supplement, 3, 319-320 (2003)
Tomari, Y., Suzuki, T. and Ueda, T.
tRNA Recognition by CCA-adding enzyme.
Nucleic Acids Research Supplement, 2, 77-78 (2002)
Shimada, N., Matsuzaki, R., Suzuki, T., Suzuki, T. and Watanabe, K.
Quality control of translation through the kinetic discrimination of tRNAs in the network of aminoacyl-tRNA synthetases.
Nucleic Acids Research Supplement, 2, 79-80 (2002)
Wada T., Shimazaki T., Nakagawa S., Otuki T., Kurata S., Suzuki .T, Watanabe K., Saigo K.
Chemical synthesis of novel taurine-containing uridine derivatives.
Nucleic Acids Research Supplement, 2, 11-12 (2002)
Suzuki, T., Suzuki, T., Wada, T., Saigo, K. and Watanabe, K.
Novel Taurine-Containing Uridine Derivatives and mitochondrial human disease.
Nucleic Acids Research Supplement, 1, 257-258 (2001)
Hanada, T., Suzuki, T. and Watanabe, K.
Translation activity of mitochondrial tRNA with unusual secondary structure.
Nucleic Acids Symposium Series., 44, 249-250 (2000)
Hori, H., Suzuki, T., Sugawara, K., Inoue, Y., Shibata, T., Kuramitsu, S.,Yokoyama, S., Oshima, T. and Watanabe, K. Identification of Thermus thermophilus HB8 tRNA (Gm18) methyltransferase gene.
Nucleic Acids Symposium Series., 44, 167-168 (2000)
Yasukawa, T., Suzuki, T., Ueda, T., Hayashi, J., Ohta, S. and Watanabe, K.
Stability of mitochondrial tRNA molecules with pathogenic point mutations.
Nucleic Acids Symposium Series., 39, 257-258 (1998)
Ueda, T., Suzuki, T. and Watanabe, K. Polysemous codon.
Nucleic Acids Symposium Series., 35, 213-214 (1996)

Book

鈴木勉「拡がるRNAの世界」『化学と工業』日本化学会 , vol. 75, 2022
大平高之, 蓑輪恵一「極限環境生物が持つ可逆的なRNAリン酸化修飾とその機能」『化学と工業』日本化学会 , vol. 75, 2022
大平高之, 蓑輪恵一, 鈴木勉「RNA修飾によるエピトランスクリプトミクス制御と生命現象」『実験医学増刊セントラルドクマの新常識』羊土社, vol.40(12), 2022
鈴木勉「RNAの可逆的なリン酸化修飾を発見」『Nature ダイジェスト』vol. 19（９月号）, 2022
鈴木勉「RNA修飾によるエピトランスクリプトミクス制御と疾患」『疾患原因遺伝子・タンパク質の解析技術と創薬/診断技術への応用』技術情報協会, 2022
鈴木勉「総論エピトランスクリプトミクス―RNA修飾の世界―」『月刊「細胞」特集エピトランスクリプトミクス』（鈴木勉編）ニュー・サイエンス社, vol. 53（12月号), 2021
穐近慎一郎，鈴木勉「m6A修飾の機能と生物学的意義」『月刊「細胞」特集エピトランスクリプトミクス』（鈴木勉編）ニュー・サイエンス社, vol. 53（12月号), 2021
鈴木健夫，鈴木勉「RNA修飾と疾患」『月刊「細胞」特集エピトランスクリプトミクス』（鈴木勉編）ニュー・サイエンス社, vol. 53（12月号), 2021
鈴木勉「アーキアにおける遺伝暗号解読機構：アグマチジンの生合成とAUAコドンの解読」『化学と生物』日本農芸化学会, vol. 50(1), pp. 36-43, 2012
鈴木勉, 鈴木健夫「ミトコンドリア脳筋症とtRNAのタウリン修飾欠損」『細胞工学特集 RNAプロセシング異常―RNA病を斬る』学研メディカル秀潤社, vol. 29(2), pp.137-143, 2010
櫻井雅之, 鈴木勉「転写後修飾によるRNA機能制御」『細胞工学　特集　特集眠りから覚めたRNA―いま明らかになるnon-coding RNAの新機能』秀潤社, vol. 28(2), 2009
宮内健常, 鈴木勉「大腸菌からのRNA抽出」『RNA実験ノート上：RNAの基本的な取り扱いから解析手法まで』羊土社, pp. 17-20, 2008
鈴木健夫, 鈴木勉「質量分析法を用いたRNA修飾ヌクレオシドの解析」『RNA実験ノート上：RNAの基本的な取り扱いから解析手法まで』羊土社, pp. 177-181, 2008
加藤敬行, 鈴木勉「有効なsiRNAのデザインと細胞への導入」『RNA実験ノート下：小分子RNAの解析からRNAiへの応用まで』羊土社, pp. 99-102, 2008
渡辺公綱, 浅井潔, 鈴木勉, 廣瀬哲郎「RNAとゲノム（最近の話題）―座談会機能性RNA研究の展望－」『ゲノム医学』メディカルレビュー社, vol.7(2), pp. 79-84, 2007
鈴木勉, 鈴木健夫, 上田宏生, 宮内健常, 坂口裕理子「マススペクトロメトリーによるncRNAの解析」『蛋白質核酸酵素（12月号増刊）　RNAと生命』共立出版, vol. 51(16), 2006
野間章子, 鈴木勉「RNA修飾酵素の細胞内局在とRNA成熟化機構」『蛋白質核酸酵素（11月号増刊）　細胞核の世界』共立出版, vol. 51(14), 2006
池内与志穂, 鈴木勉「タンパク3000プロジェクト個別的解析プログラム｢転写・翻訳｣：RNA修飾酵素の網羅的探索と機能・構造解析」『タンパク3000プロジェクト　ニュースレター』文部科学省, no. 6, 2006
鈴木勉, 鈴木健夫, 坂口裕理子「RNAマススペクトロメトリー」メディカルレヴュー社 , 2006
渡辺公綱, 鈴木勉「遺伝暗号の変遷と進化的普遍性」『蛋白質核酸酵素』共立出版, vol. 51(7), pp. 844-852, 2006
池内与志穂, 鈴木勉「RNA修飾に関わる硫黄リレータンパク質群の同定」『細胞工学』秀潤社, vol. 25(4), pp. 400-401, 2006
鈴木勉「RNA修飾の世界―見過ごされているRNAの質的な情報」『生化学』日本生化学会, vol. 77(12), pp. 1481-1496, 2005
北原圭, 鈴木勉「リボソームの立体構造と抗生物質の作用機所」『RNA工学の最前線』（中村義一　監修）シーエムシー出版 , 2005
鈴木勉, 廣瀬哲郎「機能性RNA研究におけるRNAプロセシングの重要性」『実験医学特集（７月号）解明が進むRNAの成熟化プロセス』（鈴木勉, 廣瀬哲郎　監修）羊土社, vol. 23 (12), 2005
鈴木勉「RNA修飾の生合成と機能」『実験医学特集（7月号）　解明が進むRNAの成熟化プロセス』（鈴木勉, 廣瀬哲郎監修）羊土社, vol. 23 (12), 2005
長尾翌手可, 鈴木勉「タンパク3000プロジェクト個別的解析プログラム｢転写・翻訳｣：aaRS-tRNAネットワークと翻訳精度維持機構」『タンパク3000プロジェクト　ニュースレター』文部科学省, no. 5, 2005
鴫成実, 鈴木勉「哺乳動物ミトコンドリアの翻訳系―ミトコンドリアゲノムの縮小によってもたらされたユニークなシステム」『蛋白質核酸酵素（11月号増刊）二層膜オルガネラの遺伝学』共立出版, vol. 50(14, 2005
桐野陽平, 鈴木勉「MELASにおけるA3243G変異とtRNA修飾異常」『臨床検査』医学書院, 2005
鈴木勉, 加藤敬行「RNAiにおけるsiRNAの合理的配列設計法」『RNAi法とアンチセンス法―RNAの科学と応用』講談社サイエンティフィク, 2005
鈴木勉「RNA干渉による新しい遺伝子発現制御技術と創薬」『テクノニュースちば』千葉県産業振興センター技術振興部新事業支援グループ編（千葉県産業支援技術研究所監修）, 2005
鈴木勉, 池内与志穂, 鈴木健夫「機能性RNAのマススペクトロメトリー」『実験医学創刊　躍進するRNA研究：進展する構造解析，機能性RNAの多彩な役割の解明とRNAiなど生命・医工学への応用』羊土社, vol.22 (17) , 2004
鈴木勉, 加藤敬行「in vitro転写による新規siRNA合成法とRNAi活性予測アルゴリズムの開発」『実験医学別冊　改訂　RNAi実験プロトコール』羊土社, pp. 195-207, 2004
鈴木勉, 加藤敬行「新規転写合成法を用いたsiRNAの高効率調製法」『最新医学　RNA工学の医学への展開』最新医学社, vol. 59(8), 2004
加藤敬行, 鈴木勉「siRNA予測アルゴリズムの開発」『最新医学　RNA工学の医学への展開』最新医学社, vol. 59(8), 2004
鈴木勉, 渡辺公綱「リボヌクレオームとの融合-RNAの機能異常と疾患」『遺伝子医学MOOK　疾患プロテオミクスの最前線』メディカルドゥ, ２号, 2004
鈴木勉「タンパク3000プロジェクト個別的解析プログラム｢転写・翻訳｣：ミトコンドリア翻訳関連因子の構造解析」『タンパク3000プロジェクト　ニュースレター』文部科学省, no. 3, 2004
鈴木勉「ミトコンドリアtRNAのタウリン修飾と疾患」『医学のあゆみ　ミトコンドリア─最新トピックス』医歯薬出版, vol. 209 (13), 2004
鈴木勉「変異tRNAの修飾欠損とミトコンドリア病の発症機構」『Molecular Medicine : 分子医学を臨床へ』中山書店, vol. 41 (3), pp. 291-298, 2004
鈴木勉「新規転写合成siRNAとRNAi活性予測アルゴリズムの開発」『特集バイオ・医学の世界を変える小さなRNA』バイオインダストリー, vol. 21(1), pp. 25-35, 2004
鈴木勉「序論　リボヌクレオーム：広がる転写後プロセシングの世界」『細胞工学特集　リボヌクレオーム：機能性RNAが活躍する転写後の世界」（鈴木勉監修）秀潤社, vol. 22 (9), pp. 936-938, 2003
池内与志穂, 鈴木勉「リボヌクレオーム解析：RNA修飾遺伝子の網羅的探索」『細胞工学』秀潤社, vol. 22(9), pp. 945-950, 2003
鈴木勉, 桐野陽平, 渡辺公綱「RNA修飾異常と疾患」『細胞工学』秀潤社, vol. 22(9), pp. 969-973, 2003
鈴木勉「遺伝子の多型が個性を作る」『化学と教育』日本化学会, vol. 51(7), pp. 402-405, 2003
鈴木勉「タンパク3000プロジェクト個別的解析プログラム｢転写・翻訳｣：ミトコンドリア翻訳関連因子の構造解析」『タンパク3000プロジェクト　ニュースレター』文部科学省, no. 1, pp. 51-53, 2003
鈴木勉「SSER法の開発とリボソーム研究への応用」『RNA Network Newsletter』文部科学省, vol. 2 (1), pp. 94-96, 2003
鈴木勉「トピックス編6：リボソーム(ribosome is ribozyme)」『わかる実験医学シリーズ　RNAがわかる』羊土社, pp.130-136
鈴木勉「LOBBY：2002年度ノーベル化学賞」『からだの科学』vol. 229（3月号）日本評論社, 2003
渡辺公綱, 大槻高史, 鈴木勉「ミトコンドリアの翻訳システム」『蛋白質核酸酵素(3月増刊号)：RNAの細胞生物学』共立出版,　vol. 48(4), pp. 365-374, 2003.
渡辺公綱, 鈴木勉, 姫野俵太「第2章遺伝情報の保持と伝達＿3. 翻訳」『分子生物学イラストレイテッド」（改定第2版）羊土社、pp. 56-64, 2002
鈴木　勉, 渡辺公綱「リボソームRNA(rRNA)の生合成とリボソームの構造」『日本臨床特集　ミトコンドリアとミトコンドリア病』日本臨牀社, vol. 60(増刊号4), pp. 41-45, 2002
安川武宏, 鈴木　勉, 太田茂男, 渡辺公綱「変異ミトコンドリアtRNAの修飾欠損とdecoding異常」日本臨床特集　ミトコンドリアとミトコンドリア病』日本臨牀社, vol. 60(増刊号4), pp. 197-201, 2002
鈴木　勉, 渡辺公綱「5-5. リボヌクレオーム解析」『現代科学　増刊　プロテオミクス―方法とその病態解析への応用―』東京化学同人, vol. 42, pp. 65-69, 2002
鈴木　勉「リボソーム研究の新しい潮流―リボソームミーティングに参加して―」『RNA Network Newsletter』文部科学省, vol. 1 (1), pp. 18-19, 2002
鈴木勉, 渡辺公綱「リボソームはリボザイムであった―X線結晶構造解析が解き明かすペプチド転移反応のメカニズム―」『蛋白質核酸酵素』共立出版, vol. 46(9), pp. 1268-1276, 2001
鈴木勉, 渡辺公綱「リボソームの構造機能研究の最先端―X線結晶構造解析が解き明かしたリボソームの機能―」『蛋白質核酸酵素 (8月増刊号) 新世紀における蛋白質科学の進展』共立出版, vol. 46, pp. 1635-1644, 2001
渡辺公綱, 鈴木勉「第4章ミトコンドリアtRNAの特異構造と翻訳特性」『RNA研究の最前線』(志村令郎, 渡辺公綱共編) シュプリンガー・フェアラーク東京株式会社, 2000
渡辺公綱, 鈴木勉「タンパク質の誕生～遺伝情報の翻訳の謎」『シリーズ・バイオサイエンスの新世紀２：タンパク質の一生―タンパク質の誕生、成熟から死まで』（中野明彦, 遠藤斗志也, 日本生化学会　共編）共立出版, 2000
渡辺公綱, 鈴木勉「生命の起源－RNAワールド仮説」『生物の科学　遺伝：地球の進化・生命の進化』裳華房, 別冊（12）, 2000
鈴木勉「核酸の検出と定量」『基礎生化学実験法4巻：核酸･遺伝子実験I(基礎編)』（日本生化学会編）東京化学同人, 2000
鈴木勉, 渡辺公綱「リボヌクレオームの世界－RNA転写後修飾の機能－」『バイオインダストリー』シーエムシー出版, vol. 17(11), 2000
鈴木勉「ミトコンドリアへのRNAの輸送：メカニズムの解明と医学生物学的意義」Newsletter Research on HFSP in Japan（理化学研究所S）, no. 13, 1999
上田卓也，鈴木勉，渡辺公綱「多義語コドンの発見－複数のアミノ酸と結合するファジーなtRNA－」『蛋白質核酸酵素』共立出版, vol. 42(11), pp.1815-1827, 1997

Publication (* corresponding author)

2005

Ote, T., Hashimoto, M., Ikeuchi, Y., Suetsugu, M., Suzuki, T., Katayama, T. and Kato, J. Involvement of the Escherichia coli folate-binding protein YgfZ in RNA modification and regulation of chromosomal replication initiation
Mol Microbiol., 59, 265-275 (2005)
Zhang, L., Ching Ging, N., Komoda, T., Hanada, T., Suzuki, T.* and Watanabe, K. Antibiotic susceptibility of mammalian mitochondrial translation
FEBS Lett., 579, 6423-6427 (2005)
Ikeuchi, Y., Soma, A., Ote, T., Kato, J., Sekine, Y. and Suzuki, T.* Molecular mechanism of lysidine synthesis that determines tRNA identity and codon recognition
Mol Cell., 19, 235-246 (2005)
Chimnaronk, S., Jeppesen, M.G., Suzuki, T., Nyborg, J. and Watanabe, K. Dual Mode Recognition of Noncanonical tRNAs^Ser by Seryl-tRNA Synthetase in Mammalian Mitochondria
EMBO J., 24, 3369-3379 (2005)
Kirino, Y., Goto, Y., Campos, Y., Arenas, J. and Suzuki, T.* Specific correlation between tRNA taurine-modification deficiency and clinical features of human mitochondrial disease
Proc. Natl. Acad. Sci. USA., 102, 7127-7132 (2005)
Nakanishi, K., Fukai, S., Ikeuchi, Y., Soma, A., Sekine, Y., Suzuki, T. and Nureki, O. Structural basis for lysidine formation by ATP pyrophosphatase accompanied with a lysine-specific loop and a tRNA-recognition domain
Proc. Natl. Acad. Sci. USA., 102, 7487-7492 (2005)
Yasukawa, T., Kirino, Y., Ishii, N., Holt, I.J., Jacobs, H.T., Makifuchi, T., Fukuhara, N., Ohta, S., Suzuki, T.* and Watanabe, K. Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases
FEBS Lett., 579, 2948-2952 (2005)
Sakurai, M., Ohtsuki, T., Suzuki, T. and Watanabe, K. Unusual usage of wobble modification in mitochondrial tRNAs of the nematode Ascaris suum.
FEBS Lett., 579, 2767-2772 (2005)
Nagaike, T., Suzuki, T.*, Katoh, T. and Ueda, T. Human mitochondrial mRNAs are stabilized with polyadenylation regulated by mitochondria-specific poly(A) polymerase and polynucleotide phosphorylase
J. Biol. Chem., 280, 19721-19727 (2005)
Kirino, Y. and Suzuki, T.* Human Mitochondrial Diseases Associated with tRNA Wobble Modification Deficiency
RNA biol., 2, 41-44 (2005)
Suzuki, T. Biosynthesis and function of tRNA wobble modifications. In Fine-tuning of RNA functions by modification and editing
Topics in Current Genetics, vol 12, Springer-Verlag, NY pg 24-69 (2005)
Umeda, N., Suzuki, T., Yukawa, M., Ohya, Y., Shindo, H., Watanabe, K. and Suzuki, T.* Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs: Implications for the molecular pathogenesis of human mitochondrial diseases.
J. Biol. Chem., 280, 1613-1624 (2005)

2004

Okamoto, H., Watanabe, K., Ikeuchi, Y., Suzuki, T., Endo, Y. and Hori, H. Substrate tRNA recognition mechanism of tRNA (m⁷G46) methyltransferase from Aquifex aeolicus
J. Biol. Chem., 279, 49151-49159 (2004)
Kirino, Y., Yasukawa, T., Ohta, S., Akira, S., Ishihara, K., Watanabe, K. and Suzuki, T.* Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease
Proc. Natl. Acad. Sci. USA., 101, 15070-15075 (2004)
Sato, N. S., Suzuki, T., Ueda, T., Watanabe, K., Hirata, R. D. and Hirata, M. H. Recombinant antigen-based immuno-slot blot method for serodiagnosis of syphilis.
Braz J Med Biol Res., 37(7), 949-955 (2004)
Chimnaronk, S., Jeppesenb, M.G., Shimada, N., Suzuki, T., Nyborg, J. and Watanabe, K. Crystallization and preliminary X-ray diffraction study of mammalian mitochondrial Seryl-tRNA synthetase.
Acta Crystallographica Section D, 60, 1319-1322 (2004)
Nakai, Y., Umeda, N., Suzuki, T., Nakai, M., Hayashi, H., Watanabe, K. and Kagamiyama, H. Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs.
J. Biol. Chem., 279, 12363-12368 (2004)
Hino, N., Suzuki, T., Yasukawa, T., Seio, K., Watanabe, K. and Ueda, T. The pathogenic A4269G mutation in human mitochondrial tRNAIle alters the T-stem structure and decreases the binding affinity of elongation factor Tu
Genes Cells, 9, 243-252 (2004)
Terasaki, M., Suzuki, T.*, Hanada, T. and Watanabe, K. Functional compatibility of elongation factors between mammalian mitochondrial and bacterial ribosomes: Characterization of GTPase activity and translation elongation by hybrid ribosomes bearing heterologous L7/12 proteins
J. Mol. Biol., 336, 331-342 (2004)
Limongelli, A., Schaefer J., Jackson, S., Invernizzi, F., Kirino, Y., Suzuki, T., Reichmann, H. and Zeviani, M. Variable penetrance of a familial progressive necrotizing encephalopathy due to a novel tRNA^Ile homoplasmic mutation in the mitochondrial genome
J Med Genet, 41, 342-349 (2004)
Suzuki, T., Ohtsuki, T. and Watanabe, K. Glimpses of transitions from the RNA world to the RNP world in protein compensation for RNA deficit in animal mitochondrial translation systems.
Endocytobiosis Cell Res, 15, 110-122 (2004)

2003

Kurata, S., Ohtsuki, T., Suzuki, T. and Watanabe, K. Quick two-step RNA ligation employing periodate oxidation.
Nucleic Acids Res., 31, e145 (2003)
Soma, A., Ikeuchi, Y., Kanemasa, S., Kobayashi, K., Ogasawara, N., Ote, T., Kato, J., Watanabe, K., Sekine, Y. and Suzuki, T.* An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA.
Mol Cell, 12, 689-698 (2003)
Ying, B., Suzuki, T., Shimizu, Y. and Ueda, T. A novel screening system for self-mRNA targeting proteins.
J. Biochem., 133, 485-491 (2003)
Tomari, Y., Hino, N., Nagaike, T., and Suzuki, T.* and Ueda, T. Decreased CCA-addition of human mitochondrial tRNAs bearing pathogenic A4317G or A10044G mutation.
J. Biol. Chem., 278, 16828-16833 (2003)
Kamiya, N., Tanaka, T., Suzuki, T., Takezawa, T., Takeda, S., Watanabe, K. and Nagamune, T. S-peptide as a potent peptidyl linker for protein crosslinking by microbial transglutaminase from Streptomyces mobaraensis.
Bioconjugate Chemistry 14, 351-357 (2003)
Kaneko, T., Suzuki, T., Kapushoc, S.T., Rubio, M.A., Ghazvini, J., Watanabe, K., Simpson, L. and Suzuki, T.* Wobble modification differences and subcellular localization of tRNAs in Leishmania tarentolae: implication for tRNA sorting mechanism.
EMBO J., 22, 657-667 (2003)

2002

Suzuki, T., Suzuki, T.*, Wada, T., Saigo K. and Watanabe, K. Taurine as a constituent of mitochondrial tRNAs: New insights into the functions of taurine and human mitochondrial diseases.
EMBO J., 21, 6581-6589 (2002)
Shigi, N., Suzuki, T., Tamakoshi, M., Oshima, T. and Watanabe, K. The conserved bases in TYC loop of tRNA are determinants for Thermophile-specific 2-thiolation of U54.
J. Biol. Chem., 277, 39128-39135 (2002)
Cho, H. D., Tomita, K., Suzuki, T. and Weiner, A. M. U2 snRNA is a substrate for the CCA-adding enzyme (tRNA nucleotidyltransferase)
J. Biol. Chem., 277, 3447-3455 (2002)
Toompuu, M., Yasukawa, T., Suzuki, T., Hakkinen, T., Spelbrink, J.N., Watanabe, K. and Jacobs, H.T. The 7472insC mitochondrial DNA mutation impairs the synthesis and extent of aminoacylation of tRNA^Ser(UCN) but not its structure or rate of turnover.
J. Biol. Chem., 277, 22240-22250 (2002)
Yasukawa, T., Suzuki, T., Ohta, S. and Watanabe, K. Wobble modification defect suppresses translational activity of tRNAs with MELAS an MERRF mutations.
Mitochondrion, 2, 129-141 (2002)
Suzuki, T., Ohtsuki, T., Watanabe, Y., Terasaki, M., Hanada, T. and Watanabe, K. Structural and functional compensation by proteins for the RNA deficit of animal mitochondrial translation systems.
Cell-Free Translation Systems, Chapter 17, p183-196 (Eds. Spirin, A. et al., Springer) (2002)
Hori, H., Suzuki, T., Sugawara, K., Inoue, Y., Shibata, T., Kuramitsu, S., Yokoyama, S., Oshima, T. and Watanabe, K. Identification and Characterization of Thermus thermophilus HB8 tRNA-(Gm¹⁸)-methyltransferase; Domain Structure and Conserved Amino Acid Sequence Motifs in the Enzyme.
Genes Cells, 7, 259-272 (2002)

2001

Yasukawa, T., Suzuki, T., Ishii, N., Ohta, S. and Watanabe, K. Wobble modification defect in tRNA disturbs codon-anticodon interaction in a mitochondrial disease.
EMBO J., 20, 4794-4802 (2001)
Suzuki, T.*, Terasaki, M., Takemoto-Hori, C., Hanada, T., Ueda, T., Wada, A.　and Watanabe, K. Structural compensation for deficit of rRNA with proteins in mammalian mitochondrial ribosome; systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria.
J. Biol. Chem., 276, 21724-21736 (2001)
Suzuki, T.*, Terasaki, M., Takemoto-Hori, C., Hanada, T., Ueda, T., Wada, A. and Watanabe, K. Proteomic Analysis of the Mammalian Mitochondrial Ribosome; Identification of protein components in the 28S Small Subunit.
J. Biol. Chem., 276, 33181-33195 (2001)
Nagaike, T., Suzuki, T.*, Tomari, Y., Takemoto-Hori, C., Negayama, F., Watanabe, K. and Ueda, T. Identification and Characterization of Mammalian Mitochondrial tRNA-Nucleotidyltransferases.
J. Biol. Chem., 276, 40041-40049 (2001)
Shimada, N., Suzuki, T. and Watanabe, K. Dual mode recognition of two isoacceptor tRNAs by mammalian mitochondrial seryl-tRNA synthetase.
J. Biol. Chem., 276, 46770-46778 (2001)
Yokobori, S, Suzuki, T. and Watanabe, K. Genetic code variations in mitochondria: tRNA as a major determinant of genetic code plasticity.
J. Mol. Evol., 53, 314-326 (2001)
Kenmochi, N., Suzuki, T., Uechi, T., Magoori, M., Kuniba, M., Higa, S., Watanabe, K. and Tanaka, T. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.
Genomics, 77, 65-70 (2001)
Hanada, T., Suzuki, T., Yokogawa, T., Takemoto-Hori, C., Sprinzl, M. and Watanabe, K. Translation ability of mitochondrial tRNAs^Ser with unusual secondary structures in an in vitro translation system of bovine mitochondria.
Genes Cells, 6, 1019-1030 (2001)
Shimizu, Y., Inoue, A., Tomari, Y., Suzuki, T., Yokogawa, T., Nishikawa, K. and Ueda, T. Cell-free translation reconstituted with purified components.
Nature Biotechnology, 19, 751-755 (2001)

2000

Yasukawa, T., Suzuki, T., Suzuki, T., Ueda, T., Ohta, S. and Watanabe, K. Modification Defect at Anticodon Wobble Nucleotide of Mitochondrial tRNAs^Leu(UUR) with Pathogenic Mutations of Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like Episodes.
J. Biol. Chem., 275, 4251-4257 (2000)
Yasukawa, T., Suzuki, T., Ishii, N., Ueda, T., Ohta, S. and Watanabe, K. Defect in Modification at the Anticodon Wobble Nucleotide of Mitochondrial tRNA^Lys with the MERRF Encephalomyopathy Pathogenic Mutation.
FEBS Lett., 467, 175-178 (2000)
Tin, O. F., Rykunova, A. I., Muranova, T. A., Toyoda, T., Ito, K., Suzuki, T., Watanabe, K., Garber, M. B. and Nakamura, Y. Proteolytic fragmentation of polypeptide release factor 1 of Thermus thermophilus and crystallization of the stable fragments.
Biochimie, 82, 765-772 (2000)
Yokogawa, T., Shimada, N., Takeuchi, N., Benkowski, L., Suzuki, T., Omori, A., Ueda, T., Nishikawa, K., Spremulli, L. and Watanabe K. Characterization and tRNA recognition of mammalian mitochondrial Seryl tRNA synthetase.
J. Biol. Chem., 275, 19913-19920 (2000)
Tomari, Y., Suzuki, T.*, K Watanabe, K. and Ueda, T. Role of tightly bound ATP in Escherichia coli tRNA nucleotidyltransferase.
Genes Cells, 5, 689-698 (2000)
Yasukawa, T., Hino, N., Suzuki, T., Watanabe, K., Ueda, T. and Ohta, S. A pathogenic point mutation reduces stability of mitochondrial mutant tRNA^Ile.
Nucleic Acids Res., 28, 3779-3784 (2000)
Watanabe, K. and Suzuki, T. Genetic code and its Variants.
the Encyclopedia of Life Science, (Macmillan Publishers Ltd) (2000)
Sato, N. S., Suzuki, T., Hirata M. H., Hirata, R. D. C., Ueda, T., Watanabe, K., Zerbini, L. C. M. S., Silveira, E. P. R., Melo, C. S. and Ueda, M. Novel immunoblot treponemal assay using recombinant antigens for immunodiagnosis of syphilis.
Journal Brasileiro de Patologia, 36, 161-165 (2000)

-1999

Kondow, A., Suzuki, T., Yokobori, S., Ueda, T. and Watanabe, K. An extra tRNA^Gly(U*CU) found in ascidian mitochondria responsible for decoding non-universal codons AGA/AGG as glycine.
Nucleic Acids Res., 27, 2554-2559 (1999)
Suzuki, T., Suzuki, T., Ueda, T. and Watanabe, K. High sensitive analysis of modified nucleosides by LC/MS using ESI / iontrap mass spectrometry.
J. Mass Spectrom. Soc. Jpn., 47, 168-176 (1999)
Suzuki, T., Ueda, T. and Watanabe, K. The 'polysemous' codon - a codon with multiple amino acid assignment caused by dual specificity of tRNA identity.
EMBO J., 16, 1122-1134 (1997)
Suzuki, T., Ueda, T. and Watanabe, K. A new method for identifying the amino acid attached to a particular RNA in the cell.
FEBS Lett., 381, 195-198 (1996)
Suzuki, T., Ueda, T., Yokogawa, T., Nishikawa, K. and Watanabe, K. Characterization of serine and leucine tRNAs in an asporogenic yeast Candida cylindracea and evolutionary implication of genes for tRNASerCAG responsible for translation of a non-universal genetic code.
Nucleic Acids Res., 22, 115-123 (1994)
Ueda, T., Suzuki, T., Yokogawa, T., Nishikawa, K. and Watanabe, K. Unique structure of new serine tRNAs responsible for decoding leucine codon CUG in various Candida species and their putative ancestral tRNA genes.
Biochimie, 76, 1217-1222 (1994)
Suzuki, T., Ueda, T., Ohama, T., Osawa, S. and Watanabe, K. The gene serine tRNA having anticodon sequence CAG in a pathogenic yeast, C. albicans.
Nucleic Acids Res., 21, 356 (1993)
Watanabe, K., Ueda, T., Yokogawa, T., Suzuki, T., Nishikawa, K., Mori, M., Ohama, T., Nakabayashi, H., Nakase, T. and Osawa, S. Molecular mechanism of the genetic code variations found in Candida species and its implications in evolution of the genetic code.
The Translational Apparatus Structure, Function, Regulation, Evolution (Nierhaus, K. H. et al. eds), Plenum, New York, pp647-656 (1993)
Ohama, T., Suzuki, T., Mori, M., Osawa, S., Ueda, T., Watanabe, K. and Nakase, T. Non-universal decoding of the leucine codon CUG in several Candida species.
Nucleic Acids Res., 21, 4039-4045 (1993)
Yokogawa, T., Suzuki, T., Ueda, T., Mori, M., Ohama, T., Kuchino, Y., Yoshinari, S., Motoki, I., Nishikawa, K., Osawa, S. and Watanabe, K. Serine tRNA complementary to the nonuniversal serine codon in Candida cylindracea : Evolutionary implications.
Proc.Natl. Acad. Sci. USA., 89, 7408-7411 (1992)